A Case of Muir-Torre Syndrome.
10.3341/jkos.2011.52.3.355
- Author:
Kunho BAE
1
;
Yoon Duck KIM
;
Kyung In WOO
Author Information
1. Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. eyeminded@hanmail.net
- Publication Type:Case Report
- Keywords:
Eyelid tumor;
Muir-Torre syndrome;
Sebaceous;
Systemic malignancy
- MeSH:
Adenoma;
Aged;
Anesthesia, Local;
Biopsy;
Diagnosis, Differential;
Endometrial Neoplasms;
Eyelids;
Female;
Humans;
Hysterectomy;
Muir-Torre Syndrome;
Sebaceous Glands;
Sigmoid Neoplasms;
Skin;
Skin Neoplasms
- From:Journal of the Korean Ophthalmological Society
2011;52(3):355-358
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To present a rare case of Muir-Torre syndrome characterized by the association of sebaceous skin tumors and systemic malignancies. CASE SUMMARY: A 65-year-old female visited our clinic with an irregular nodular mass of the right lower eyelid, which developed 1 year earlier. An excisional biopsy and lower lid reconstruction with Tenzel's semicircular rotational flap was performed under local anesthesia. Histopathologic examination showed well-differentiated sebaceous cells, consistent with sebaceous adenoma. The patient had undergone total abdominal hysterectomy and lower anterior resection due to endometrial cancer and sigmoid colon cancer 5 years before, and nephroureterectomy due to papillary urothelial carcinoma 3 years before. Based on the history of systemic malignancy and sebaceous skin cancer, a diagnosis of Muir-Torre syndrome was made. CONCLUSIONS: When a sebaceous gland tumor of the eyelids is detected, Muir-Torre syndrome should be included in the differential diagnosis, and systemic work-up for the internal malignancy must be performed.
