Observation on treatment of ectopic pregnancy by combination therapy of Chinese herbal medicine with mifepristone or methotrexate.
- Author:
Ying SU
1
;
Yan SUN
;
Lan MA
Author Information
- Publication Type:Clinical Trial
- MeSH: Abortifacient Agents; therapeutic use; Adult; Drug Therapy, Combination; Drugs, Chinese Herbal; therapeutic use; Female; Humans; Methotrexate; therapeutic use; Mifepristone; therapeutic use; Phytotherapy; Pregnancy; Pregnancy, Ectopic; drug therapy
- From: Chinese Journal of Integrated Traditional and Western Medicine 2002;22(6):417-419
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo find a simpler, effectiver with less side-effect method for treatment of ectopic pregnancy.
METHODSOne hundred and fourteen patients of ectopic pregnancy were divided into two groups, the 56 patients in Group A were treated with Mifepristone and Chinese herbal medicine (CHM), and 58 patients in Group B were treated with Methotrexate and CHM. The therapeutic effect in both groups was observed and compared.
RESULTSThe rate of success in Group A was 82.14% and in Group B 70.69%, comparison between them showed no significance (P > 0.05). Time for successful treatment was 14.54 +/- 5.87 days in Group A and 9.00 +/- 5.09 days in Group B, comparison of them showed significant difference (P < 0.01). Insignificance revealed in comparison between the occurrence of side-effects for the groups, such as nausea, vomiting, diarrhea, liver dysfunction and lowering of white blood cells, but significance was shown in re-menstruation time (43.43 +/- 1.77 days vs 38.38 +/- 1.13 days, P < 0.05).
CONCLUSIONTreatments of combined CHM with Mifepristone or Methotrexate showed similar therapeutic effect in treating ectopic pregnancy, but the latter showed a quicker initiation and less side-effects in delaying the re-menstruation time.
