Effect of jiawei mojie tablet on plasma oxytocin level in patients with primary dysmenorrhea in menstrual period.
- Author:
Hai-xia DENG
1
;
Nan-sun ZHU
;
Cai-wen WANG
Author Information
- Publication Type:Clinical Trial
- MeSH: Adolescent; Adult; Drugs, Chinese Herbal; therapeutic use; Dysmenorrhea; blood; drug therapy; Female; Humans; Oxytocin; blood; Tablets
- From: Chinese Journal of Integrated Traditional and Western Medicine 2003;23(5):354-356
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the therapeutic mechanism of Jiawei Mojie Tablet (JMT) in treating primary dysmenorrhea (PD) by observing its effect on plasma oxytocin (OT) level in patients in menstrual period.
METHODSSixty-three patients with PD enrolled in the study were randomly divided into the JMT group (n = 33) and the control Group (n = 30, treated with Yueyueshu Granule) to observe the change of OT level in the menstrual period before and after treatment.
RESULTSOT level in patients with PD was obviously higher than that in healthy subjects (P < 0.01), and was positively correlated with the degree of pain (r = 0.738, P < 0.01). OT level reduced significantly after treatment (P < 0.01), the reduction was more significant in the JMT group than that in the control group (P < 0.01).
CONCLUSIONJMT could reduce the OT level in menstrual period.
