Beyond Hygiene: Commensal Microbiota and Allergic Diseases.
- Author:
Sung Wook HONG
1
;
Kwang Soon KIM
;
Charles D SURH
Author Information
- Publication Type:Review
- Keywords: Commensal microbiota; Food allergy; Asthma; Atopic dermatitis
- MeSH: Anti-Bacterial Agents; Asthma; Dermatitis, Atopic; Dietary Fiber; Food Hypersensitivity; Hygiene*; Intestines; Microbiota*; Physiology
- From:Immune Network 2017;17(1):48-59
- CountryRepublic of Korea
- Language:English
- Abstract: Complex communities of microorganisms, termed commensal microbiota, inhabit mucosal surfaces and profoundly influence host physiology as well as occurrence of allergic diseases. Perturbing factors such as the mode of delivery, dietary fibers and antibiotics can influence allergic diseases by altering commensal microbiota in affected tissues as well as in intestine. Here, we review current findings on the relationship between commensal microbiota and allergic diseases, and discuss the underlying mechanisms that contribute to the regulation of allergic responses by commensal microbiota.
