Impact of percutaneous coronary intervention versus medical therapy on mortality in stable coronary artery disease: a meta-analysis
10.3760/cma.j.issn.0253-3758.2014.12.014
- VernacularTitle:比较经皮冠状动脉介入治疗与药物治疗对稳定性冠心病患者预后影响的荟萃分析
- Author:
Youdong WAN
1
;
Tongwen SUN
;
Ziqi LIU
;
Shuguang ZHANG
;
Rui YAO
;
Haimu YAO
;
Quancheng KAN
Author Information
1. 450052,郑州大学第一附属医院综合重症监护室
- Keywords:
Coronary disease;
Angioplasty,transluminal,percutaneous coronary;
Drug therapy;
Prognosis
- From:
Chinese Journal of Cardiology
2014;42(12):1048-1053
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the impacts of percutaneous coronary intervention (PCI) and medical therapy on mortality in patients with stable coronary artery disease.Methods We searched PubMed,Embase,Cochrane central register of controlled trials,Wanfang data and CNKI to find relevant randomized controlled trials on PCI versus medical therapy for treating patients with stable coronary artery disease,which were reported before December 2013.Publications were selected according to inclusion and exclusion standard.Meta-analyses was performed with the software of STATA 12.0.Results Five randomized controlled trials and 5 567 patients were enrolled for this analysis.Compared with medical therapy,PCI could not significantly decrease the long-term all-cause mortality (RR =0.96,95％ CI 0.80-1.15),the cardiac death rate (RR =1.02,95％ CI 0.77-1.36),the myocardial infarction rate (RR =1.05,95％ CI 0.89-1.23),the acute coronary syndrome (RR =0.70,95％ CI 0.27-1.82),the rate of freedom from angina (RR =1.09,95％ CI0.98-1.21),and the rate of stroke (RR =1.27,95％ CI 0.75-2.15).However,the revascularization rate was significantly lower for patients in PCI group (RR =0.60,95％ CI 0.42-0.86).Conclusions Long-term mortality is similar for patients with stable coronary artery disease underwent PCI or medical therapy.
