Influences of orthodontic tooth movement on estrous cycle and estrogen in rats.
- Author:
Qing ZHAO
1
;
Zhen TAN
;
Jie GUO
;
Yang-xi CHEN
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Estrogens; blood; Estrous Cycle; physiology; Female; Rats; Rats, Wistar; Tooth Movement Techniques
- From: Chinese Journal of Stomatology 2006;41(2):90-91
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the influences of orthodontic tooth movement on estrous cycle and estrogen in female rats.
METHODSTwo hundred female rats were divided into control group, one-time activation group, four-time activation group and sham-operated group. Each group was divided again into 4 sub-groups according to the different stage of the estrous cycle. The force-loading groups received repeated intermittent force. Serum estrogen was measured and the change of estrous cycle was recorded.
RESULTSThere were significant variations in the estrogen level among the groups which received mechanical force during the same stage of the estrous cycle (P < 0.01) and among the subgroups within each group (P < 0.05). These experimental treatments affected the estrous cycle of the rats in the groups received force in metestrus and diestrus.
CONCLUSIONSEstrus of rats was the appropriate time for the orthodontic force.
