Microsurgical removal of olfactory groove meningiomas.
- Author:
Ri-Sheng LIANG
1
;
Liang-Fu ZHOU
;
Ying MAO
;
Rong ZHANG
;
Wei-Zhong YANG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Cerebrospinal Fluid Rhinorrhea; etiology; Dura Mater; pathology; surgery; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; diagnosis; pathology; surgery; Meningioma; diagnosis; pathology; surgery; Microsurgery; adverse effects; methods; Middle Aged; Neoplasm Recurrence, Local; Paranasal Sinuses; pathology; surgery; Reconstructive Surgical Procedures; Skull Base; pathology; surgery
- From: Chinese Journal of Oncology 2011;33(1):70-75
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore an effective method for further improving the surgical results of treatment of olfactory groove meningiomas.
METHODSSixty seven cases of olfactory groove meningiomas were treated by microneurosurgery, among which fifty seven were de novo cases, eight were recurrent tumors and the other two re-recurrent cases. Modified Derome approach was used in 12 cases, bilateral subfrontal approach in 28 cases, modified pterional approach in 21 cases and unilateral subfrontal approach in six cases. Tumors were resected microsurgically with radical removal of invaded dura, bone, and paranasal sinus mucosa. Reconstruction was performed in patients with skull base defect.
RESULTSSimpson grade I removal was accomplished in 59 cases, grade II in seven cases and grade IV in one case. Among 57 patients with de novo tumor, Simpson I resection was accomplished in 54 cases. Postoperative rhinorrhea and intracranial infection occurred in one case and was cured after temporal lumbar CSF drainage and antibiotic therapy. Two patients (2.9%) died within one month after operation, i.e.one aged patient of heart failure and the other of severe hypothalamus complication. Forty seven patients (72.3%) were followed up from one to ten years with an average of five years and four months. With the exception of two cases died, among the alive 45 patients, there were only three patients with tumor recurrence, which had undergone Simpson II or IV tumor resection. No recurrence was found in cases with Simpson I tumor removal. Previous blurred vision was not improved in three patients, hemiparalysis in two patients, and the other patients recovered well, resuming previous jobs or being able to take care themselves.
CONCLUSIONSTotal tumor removal (Simpson I) should be the surgical goal for treatment of olfactory groove meningiomas, especially for de novo cases. An appropriate approach is fundamental in the effort to remove an OGM totally. Appropriate anterior skull base reconstruction with vascularized material is important and mandatory.
