Onset feature and efficacy of early interventional treatment of Artemisia pollinosis
10.3760/cma.j.issn.1673-0860.2014.04.003
- VernacularTitle:蒿属花粉症的发病特点及季节前干预治疗的疗效分析
- Author:
Yuhui OUYANG
1
,
2
;
Erzhong FAN
;
Ying LI
;
Luo ZHANG
Author Information
1. 100730 首都医科大学附属北京同仁医院耳鼻咽喉头颈外科,100730
2. 北京市耳鼻咽喉科研究所鼻病研究北京市重点实验室
- Keywords:
Rhinitis,allergic,seasonal;
Artemisia;
Treatment outcome
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2014;49(4):272-276
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical feature and treatment methods of Artemisia pollinosis.Methods Skin prick test results of 14 426 cases from Beijing Tongren hospital and pollen concentration of Beijing observatory from 2007 to 2011 were analyzed to identify the clinical feature of Artemisia pollinosis patients and its correlation with the pollen concentration.Patients were given leukotriene receptor antagonists (Montelukast) for 2 weeks,followed by 4 weeks of mometasone furoate nasal spray (EIT group:n =21),or only 4 weeks of mometasone furoate nasal spray (POT group:n =16).The nasal symptom score was compared between 2 groups.SPSS 16.0 software was used to analyze the data.Results Artemisia pollinosis accounted for 30.8％ (4 442/14 426) of all SPT positive allergic rhinitis patients,and most Artemisia SPT positive results were strong positive (3 793/4 442,85.4％) ; onset age peak of Artemisia pollinosis patients was at the age of 19 to 30,onset time concentrated in August to September,was consistent with the peak period of Artemisia pollen concentration; EIT treatment using leukotriene receptor antagonists two weeks before pollen season significantly improved sneeze,sniveling and rhinocnesmus symptoms (t value was 3.28,3.92,3.09,respectively,all P ＜ 0.01) compared with post-onset treatment(POT).But nasal obstruction and cough symptoms had no significant difference between two groups (t value was 0.85,1.52,respectively,all P ＞ 0.05).Conclusion Artemisia pollen is the main pollen allergen in Beijing,EIT treatment was effective to pollinosis.
