A new steroidal alkaloid from the bulbus of Fritillaria wabuensia.
- Author:
Qian CHEN
1
;
Li-hua ZHU
;
Yun-feng XU
;
Ju-zheng FAN
Author Information
- Publication Type:Journal Article
- MeSH: Cevanes; chemistry; isolation & purification; Cyclic N-Oxides; chemistry; isolation & purification; Fritillaria; chemistry; Molecular Structure; Plants, Medicinal; chemistry; Triterpenes; chemistry; isolation & purification
- From: Acta Pharmaceutica Sinica 2004;39(5):348-350
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo investigate the chemical constituents of the bulbs of Fritillaria wabuensia.
METHODSChromatography techniques were used to isolate the chemical constituents. EI-MS, 1HNMR, 13 CNMR and DEPT were used to determine the structures of the isolated constituents.
RESULTSThree alkaloids were isolated from the bulbs of Fritillaria wabuensia, and were identified as imperialine (I), imperialine-beta-N-oxside (II), isoverticine-beta-N-oxide (III).
CONCLUSIONIsoverticine-beta-N-oxide was isolated from the bulbs of Fritillaria wabuensia for the first time. Isoverticine-beta-N-oxide is a new alkaloid.
