Water-soluble chemical constituents of Swertia davidi Franch.
- Author:
Guang-yao ZENG
1
;
Gui-shan TAN
;
Kang-ping XU
;
Xiao-ping XU
;
Fu-shuang LI
;
Jian-bing TAN
;
Gao-yun HU
Author Information
- Publication Type:Journal Article
- MeSH: Glucosides; chemistry; isolation & purification; Molecular Conformation; Molecular Structure; Plants, Medicinal; chemistry; Swertia; chemistry; Xanthones; chemistry; isolation & purification
- From: Acta Pharmaceutica Sinica 2004;39(5):351-353
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo study the active constituents of Swertia davidi Franch.
METHODSColumn chromatographies on silica gel, Sephadex LH-20 and Diaion-201 et al. were used to isolate and purify the chemical components. Their structures were identified by UV, IR, MS, NMR and 2D-NMR.
RESULTSThese compounds were elucidated as 8-O-beta-D-glucopyranosyl-1, 3, 5-trihydroxyxanthone (I), 5-O-beta-D-glucopyranosyl-1, 8-dihydroxy-3-methoxyxanthone (II), 5-O-beta-D-glucopyranosyl-1, 3, 8-trihydroxyxanthone (III) and swertamarin (IV).
CONCLUSIONCompound III is a new xanthone glucoside. The other compounds were isolated from this plant for the first time.
