Structures of four new triterpenoid saponins from the leaves of Oplopanax elatus Nakai.
- Author:
Guang-shu WANG
1
;
Xiao-hong YANG
;
Jing-da XU
Author Information
- Publication Type:Journal Article
- MeSH: Molecular Conformation; Molecular Structure; Oplopanax; chemistry; Plant Leaves; chemistry; Plants, Medicinal; chemistry; Saponins; chemistry; isolation & purification
- From: Acta Pharmaceutica Sinica 2004;39(5):354-358
- CountryChina
- Language:English
-
Abstract:
AIMIsolation and structural elucidation of the triterpenoid saponins of Oplopanax elatus Nakai.
METHODSSolvent extraction and column chromatography were used to isolate the triterpenoid saponins, physico-chemical constants and spectroscopic analysis were employed for structural elucidation.
RESULTSFour newtriterpenoid saponins named cirenshenoside S (1), cirenshenoside T (2), cirenshenoside U (3) and cirenshenoside V (4) were isolated, and their structures were elucidated to be 3-O-beta-D-glucopyranosyl 3beta,23-dihydroxylup-20 (29)-en-28-oic acid 28-O-alpha-L-rhamnopyranosyl (1 --> 4)-beta-D-glucopyranosyl (1 --> 6)-beta-D-glucopyranoside (1), 3-O-beta-D-glucopyranosyl hederagenin 28-O-alpha-L-rhamnopyranosyl (1 --> 4)-beta-D-glucopyranosyl (1 --> 6)-beta-D-glucopyranoside (2), 3-O-beta-D-glucopyranosyl 3beta-hydroxyolean-9(11),12-dien-28-oic acid 28-O-alpha-L-rhamnopyranosyl (1 --> 4)-beta-D-glucopyranosyl (1 --> 6)-beta-D-glucopyranoside (3) and 3alpha-hydroxyolean-12-dien-23,28-dioic acid 28-O-alpha-L-rhamnopyranosyl (1 --> 4 )-beta-D-glucopyranosyl (1 --> 6)-beta-D-glucopyranoside (4), respectively.
CONCLUSIONCompounds 1-4 are new triterpenoid saponins and isolated from the leaves of Oplopanax elatus Nakai for the first time.
