Two new flavonoids from the flower of Castanea mollissima Blume.

Author: Si WANG ¹ ; Wen-zhao TANG ; Xing-bao DING
Author Information

1. Institute of Materia Medica, Shandong Academy of Medical Science, Jinan 250062, China.
Publication Type:Journal Article
MeSH: Fagaceae; chemistry; Flowers; chemistry; Glucosides; chemistry; isolation & purification; Kaempferols; chemistry; isolation & purification; Mannosides; chemistry; isolation & purification; Molecular Conformation; Molecular Structure; Plants, Medicinal; chemistry
From: Acta Pharmaceutica Sinica 2004;39(6):442-444
CountryChina
Language:Chinese
Abstract:
AIMTo study the bioactive constituents from the flower of Castanea mollissima Blume.
METHODSCompounds were isolated and purified by column chromatography on silica gel and polyamide. Structures were determined by various spectroscopic data,including UV, IR, 1H and 13CNMR, EIMS and FABMS, 1H-13C-COSY and HMBC.
RESULTSTwo compounds were isolated from the ethyl acetate fraction of 95% ethanol extract and the structures were elucidated as kaempferol-3-O-[6"-(E)-p-coumaroyl]-alpha-D-mannopyranoside (1) and kaempferol-3-O-[6", 4"-di-(E)-p-coumaroyl]-alpha-D-mannopyranoside (2).
CONCLUSIONCompounds 1 and 2 are new compounds, named castanoside A and B respectirely.