The isolation and identification of two new epimer from the mother liquid of testosterone.
- Author:
Zhong-Duo YANG
1
;
You-Fu WANG
;
Li-Bo LIN
;
Yuan-Chao LI
Author Information
- Publication Type:Journal Article
- MeSH: Androstenols; chemistry; isolation & purification; Drug Contamination; Molecular Conformation; Molecular Structure; Stereoisomerism; Testosterone; chemistry
- From: Acta Pharmaceutica Sinica 2004;39(7):528-530
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo study the impurity of the drug testosterone.
METHODSChromatography methods were used to separate the chemical constituents. Their structures were determined by NMR and MS spectral analysis.
RESULTSTwo new epimers were isolated from the mother liquid of the drug.
CONCLUSIONThese new epimers were identified as 3alpha-ethoxyandrost-4-en-17beta-ol, 3beta-ethoxyandrost-4-en-17beta-ol.
