Studies on the chemical constituents of Evodia rutaecarpa (Juss.) Benth.
- Author:
Qi-zhi WANG
1
;
Jing-yu LIANG
Author Information
- Publication Type:Journal Article
- MeSH: Alkaloids; chemistry; isolation & purification; Carbolines; chemistry; isolation & purification; Evodia; chemistry; Fruit; chemistry; Indole Alkaloids; Molecular Structure; Plant Extracts; chemistry; isolation & purification; Plants, Medicinal; chemistry; Quinazolines; chemistry; isolation & purification
- From: Acta Pharmaceutica Sinica 2004;39(8):605-608
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo study the chemical constituents of Evodia rutaecarpa (Juss.) Benth.
METHODSThe crude total alkaloids were enriched by acid-base treatment and solvent extraction. Isolation and purification were carried out by silica gel column chromatography and recrystallization etc. Structural determination of the pure compounds were based on physico-chemical properties and various spectral data analysis (1HNMR, 13CNMR, UV, IR, 1H-1H COSY, HMQC, HMBC, ESIMS, HREIMS, NOESY).
RESULTSFourteen compounds were obtained from Evodia rutaecarpa, ten of them were identified as evodianinine (1), rutaecarpine (2), evodiamine (3), wuchuyuamide I (4), hydroxyevodiamine (5), limonin (6), daucosterol (7), triacontanoic acid (8), nonacosane (9) and beta-sitosterol (10).
CONCLUSIONCompound 1 is a new alkaloid named evodianinine.
