Determination of entrapment efficiency of breviscapine nanoliposomes.
- Author:
Fei XIONG
1
;
Jia-bi ZHU
;
Wei WANG
;
Xiao-bing HUA
Author Information
- Publication Type:Journal Article
- MeSH: Asteraceae; chemistry; Drug Carriers; Flavonoids; administration & dosage; chemistry; isolation & purification; Liposomes; Nanotechnology; Particle Size; Plants, Medicinal; chemistry; Technology, Pharmaceutical; methods
- From: Acta Pharmaceutica Sinica 2004;39(9):755-757
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo determine the entrapment efficiency of breviscapine nanoliposomes.
METHODSRetrodialysis method was used to determine the entrapment efficiency of breviscapine nanoliposomes. The drug recovery and the sample recovery were considered to verify the feasibility of the method.
RESULTSThe drug recovery was (99.6 +/- 0.6)%. The sample recovery was (99.9 +/- 0.8)%. The entrapment efficiency of breviscapine nanoliposomes was (75.3 +/- 2.3)%.
CONCLUSIONThe method used in this study is simple, applicable and accurate for determination of the entrapment efficiency of breviscapine nanoliposomes.
