More favorable long-term outcome after discharge in young adults with myocardial infarction.
- Author:
Bo Young CHUNG
1
;
Jong Won HA
;
Yang Soo JANG
;
Dong Hoon CHOI
;
Shin Ki AHN
;
Se Jong RIM
;
Nam Sik CHUNG
;
Won Heum SHIM
;
Seung Yun CHO
;
Sung Soon KIM
Author Information
1. Cardiology Division, Yonsei Cardiovascular Center, Yonsei University College of Medicine, Seoul, Korea. jwha@yumc.yonsei.ac.kr
- Publication Type:Original Article
- Keywords:
Myocardial infarction;
Adolescence;
Outcome assessment
- MeSH:
Adolescent;
Angioplasty, Balloon, Coronary;
Coronary Artery Bypass;
Coronary Vessels;
Disease-Free Survival;
Follow-Up Studies;
Heart Failure;
Humans;
Hypertension;
Male;
Myocardial Infarction*;
Prognosis;
Risk Factors;
Stroke;
Young Adult*
- From:Korean Journal of Medicine
2000;59(1):30-39
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The purpose of this study was to evaluate risk factors, angiographic characteristics and long-term prognosis of young adults with myocardial infarction(MI). METHODS: Of the 2,680 patients with a history of MI, there were 148 patients 40 years old(Group 1). Risk factors, angiographic characteristics, cardiac events and long-term prognosis of group 1 were compared with those of randomly selected 149 patients between 41 years to 70 years old(Group 2) for a mean follow-up duration of 38 months(1-147 months). Cardiac events include death, reinfarction, coronary artery bypass grafting, percutaneous transluminal coronary angioplasty, congestive heart failure, stroke, and angina. RESULTS: Smoker and male gender were more frequent in group 1(p<0.001). In group 2, hypertension and diabetes were more frequently observed(p<0.001). Angiographically normal coronary arteries, nonobstructive disease(<70% stenosis) and single-vessel disease were more frequent in group 1 than those in group 2 (p<0.001). There was no significant difference of overall survival at 7 years between the two groups(group 1; 95%, group 2; 89%, p>0.05). If hospital deaths were excluded, the 7-year survival was better in group 1(group 1; 99%, group 2; 92%, p<0.01). The cardiac event free survial at 7 years was not different between two groups(p>0.05). Although a better left ventricular(LV) systolic function (ejection fraction(EF) 40%) showed more favorable survival in group 2(EF40%: 94%, EF<40%: 80%, p<0.05), survival was not influenced by LV systolic function in group 1. CONCLUSION: Young patients with MI have a more favorable long-term survival after discharge compared with that of the older patients regardless of LV systolic function. Cardiac event free survival was, however, not different between two groups.
