Potassium channels and proliferation and migration of breast cancer cells.
- Author:
Lei ZHANG
1
;
Wei ZOU
;
Shi-Sheng ZHOU
;
Dong-Dong CHEN
Author Information
1. College of Life Science, Liaoning Normal University, Dalian 116029, China.
- Publication Type:Journal Article
- MeSH:
Breast Neoplasms;
pathology;
Cell Movement;
Female;
Humans;
Neoplasm Invasiveness;
Neoplasm Metastasis;
Potassium Channels;
metabolism
- From:
Acta Physiologica Sinica
2009;61(1):15-20
- CountryChina
- Language:English
-
Abstract:
Potassium channels (K(+) channels), a family of special ion channel proteins, are involved in various physiological functions. Recent data show that the abnormalities of K(+) channels are not only responsible for some neurological and cardiovascular diseases but also for channelopathies. Furthermore, many groups reported that the abnormalities of K(+) channels had shown their oncogenic potential in breast introduction and other malignant tumors, promoting proliferation, invasion and metastasis. The aim of this review is to give an updated introduction of research progress in K(+) channels associated with breast cancer.
