Effect of maximum blood pressure when discharged from the hospital on the prognosis among patients with acute ischemic stroke
10.3760/cma.j.issn.0254-6450.2015.06.024
- VernacularTitle:缺血性脑卒中患者急性期血压最大值与预后关系的研究
- Author:
Xiaoshan YANG
1
;
Ningning WANG
;
Hongzhao ZHANG
;
Jingbo ZHAO
;
Qingcheng LIANG
Author Information
1. 150081,哈尔滨医科大学公共卫生学院流行病学教研室
- Keywords:
Ischemic stroke;
Maximum blood pressure;
Discharge prognosis
- From:
Chinese Journal of Epidemiology
2015;36(6):649-652
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between maximum blood pressure and the prognosis after discharged from the hospital,among patients with ischemic stroke.Methods A cohort study was conducted which including 471 cases of ischemic stroke patients that were collected from February 2014 to December 2014 at the Second Affiliated Hospital of Harbin Medical University.Values of everyday blood pressure were measured on each patient at the first six days after admitted to the hospital.Maximum blood pressure value of the 6 days was taken as an indicator of the blood pressure levels.The ability on daily living was measured by the modified Rankin score (mRs).Data were analyzed by Chi-square test,t test and multivariate logistic regression analysis.Results Confounding factors would include age,gender,culture,physical activity,income,smoking,alcohol,hypertension,diabetes,coronary heart disease,stroke history,hospitalization mrs,lipid parameters,homocysteine and blood sugar and were adjusted.Results from multivariate logistic regression analysis showed that the maximum SBP was associated with adverse outcomes.Compared with 140-159 mmHg for SBP,OR(95％CI) was 2.51 (1.30-4.85) for 160-179 mmHg,OR (95％ CI) was 2.68 (1.27-5.65) for those pressure levels higher than 180 mmHg,after multiple factors were adjusted.Compared with 90-99 mmHg for DBP,OR(95％CI) was 1.92 (1.00-3.67) for 100-109 mmHg,OR (95％ CI) was 2.78 (1.35-5.69) for the ones higher than 110 mmHg.Conclusion Maximum blood pressure during hospitalization might be associated with adverse outcome of ischemic stroke patients.
