Compliance of antiviral therapy and influencing factors in people living with HIV/AIDS in Nanjing.

Hongxia Wei; Meng LI; Xiayan Zhang; Kai BU; Yibing Feng; Xiaoyan Liu; Ling'en Shi; Yuheng Chen; Chunqin Bai; Gengfeng FU; Xiping Huan; Email: Huanxp@vipsinacom; Lu Wang; Email: Wanglu64@163com

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Compliance of antiviral therapy and influencing factors in people living with HIV/AIDS in Nanjing.

Author: Hongxia WEI ¹ ; Meng LI ² ; Xiayan ZHANG ² ; Kai BU ² ; Yibing FENG ² ; Xiaoyan LIU ³ ; Ling'en SHI ³ ; Yuheng CHEN ³ ; Chunqin BAI ¹ ; Gengfeng FU ³ ; Xiping HUAN ⁴ ; Email: HUANXP@VIP.SINA.COM. ; Lu WANG ⁵ ; Email: WANGLU64@163.COM.
Author Information

1. No. 2 Hospital of Nanjing, Nanjing 210003, China.
2. National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention.
3. Jiangsu Provincial Center for Disease Control and Prevention.
4. Jiangsu Provincial Center for Disease Control and Prevention
5. National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention
Publication Type:Journal Article
MeSH: Acquired Immunodeficiency Syndrome; drug therapy; Age Factors; Antiretroviral Therapy, Highly Active; Antiviral Agents; adverse effects; therapeutic use; China; Disease Progression; HIV Infections; drug therapy; Humans; Medication Adherence; statistics & numerical data; Reminder Systems; Smoking; Surveys and Questionnaires
From: Chinese Journal of Epidemiology 2015;36(7):672-676
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo understand the compliance of highly active anti-retroviral therapy (HAART) and influencing factors in people living with HIV/AIDS (PLWHA) in Nanjing.
METHODSPLWHA receiving HAART in No. 2 Hospital of Nanjing during May-June 2014 were recruited in this study. Self-administrated questionnaire was used to collect the data about HAART compliance and socio-demographic characteristics of PLWHA surveyed. Descriptive and multivariate statistical analysis were conducted to examine the effects of the factors on self-reported HAART adherence.
RESULTSA total of 276 PLWHA were surveyed, According to the evaluation criterion of Center for Adherence Support Evaluation (CASE), 252 cases showed good compliance (91.3%). logistic regression analysis revealed that smoking, progress of the disease and side effects, reminding of taking drug and age were correlated with self-reported HAART adherence.
CONCLUSIONIt is suggested to strengthen the education about antiviral therapy compliance in PLWHA with mild infection and those who are smokers and young, suffer from side effects, have no reminding methods for taking drug.