Using linear discriminant analysis method basing on genetic algorithms to find out the role of clinical symptoms for taking differential diagnosis between typhoid fever and scrub typhus
- Author:
Vien Van Cao
- Publication Type:Journal Article
- Keywords:
typhoid fever
- MeSH:
Typhoid Fever;
Scrub Typhus;
diagnosis;
Algorithms
- From:Journal of Medical and Pharmaceutical Information
2001;(11):24-29
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Linear discriminant analysis method basing on genetic algorithms was used to find out the role of clinical symptoms for taking differential diagnosis between typhoid fever and scrub typhus. Clinical records of 526 patients suffering from one of those diseases were used as input data for algorithms. The results showed that the differential value of symptoms are as follows: roseola (4 points), infectious constitution (2 points), drum belly (2 points), ingestive disorder (1 points), decrease of white-blood cell count (1 point), congestion (-2 points), enlarge of lymph node (- 2 points), erythematous eruption (-3 points), eschar (-5 points). The diagnostic rule are a follows: total point >=3: typhoid fever, between 0 and 2 points: suggestion of typhoid fever, total point <=-3: scrub typhus, between o and -2 points: suggestion of scrub typhus. To re-test on 50 patients of those 526 patients randomly, the accuracy rate of this rule is at least 98%.
