Percutaneous microwave coagulation therapy for lung cancer.
- Author:
Weijian FENG
1
;
Wei LIU
;
Caiying LI
;
Zhigang LI
;
Ruxun LI
;
Fengling LIU
;
Baoe ZHAI
;
Jian SHI
;
Gaofeng SHI
Author Information
- Publication Type:Journal Article
- MeSH: Follow-Up Studies; Humans; Lung Neoplasms; complications; diagnostic imaging; pathology; therapy; Microwaves; adverse effects; therapeutic use; Survival; Time Factors; Tomography, X-Ray Computed; methods; Treatment Outcome
- From: Chinese Journal of Oncology 2002;24(4):388-390
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo evaluate the clinical effect, CT image changes and side-effects of percutaneous microwave coagulation therapy for lung cancer.
METHODSCT-guided percutaneous puncture was performed using a needle mono-pole microwave antenna with 65W, 2 450 MHz microwave delivered in 60 seconds to 20 peripheral lung cancer patients, including 8 suffering from primary lung cancer and 12 metastatic lung cancer (totally 28 lesions).
RESULTSSixteen patients were alive after having been followed-up for 3 approximately 24 months. All patients showed nodules decreased in size. Diminution of over 50% was observed in 13 nodules and 3, completely disappeared. The overall response rate was 57.1%. Ellipsoid shadow 3.5 cm x 2.5 cm across was observed by CT in lesions immediately after coagulation. Gasification within the coagulated area was observed in a week with a high density in the peripheral region. Consolidation was observed in 3 months and the lesion disappeared 1 year later. Complete tumor necrosis was proved by biopsy. No side-effects or complications were observed.
CONCLUSIONPercutaneous microwave coagulation therapy is a new safe treatment for lung cancer, giving marked effect but minimum trauma.
