A Systematic Review of the Value of Thrombelastography or Thromboelastometry for Prediction of Venous Thromboembolism.

Zhi-yun Jiang; Jun-fen MA; Qian Wang; Fan WU; Jie-dan Ping; Liang Ming

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A Systematic Review of the Value of Thrombelastography or Thromboelastometry for Prediction of Venous Thromboembolism.

Author: Zhi-Yun JIANG ¹ ; Jun-Fen MA ¹ ; Qian WANG ¹ ; Fan WU ¹ ; Jie-Dan PING ¹ ; Liang MING ²
Author Information

1. Department of Clinical Laboratorial Examination,The First Affiliated Hospital of Zhengzhou University,Key Laboratory of Laboratory Medicine of Heman Province Zhengzhou 450052,Henan Province, China.
2. Department of Clinical Laboratorial Examination,The First Affiliated Hospital of Zhengzhou University,Key Laboratory of Laboratory Medicine of Heman Province Zhengzhou 450052,Henan Province, China. E-mail: mingliang@zzu.edu.cn.
Publication Type:Journal Article
From: Journal of Experimental Hematology 2017;25(5):1498-1503
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo systematically collect the thrombelastography (TEG)-or thromboelastometry (ROTEM)-related data, and predict to evaluate their values for the prediction of thromboembolic events.
METHODSDatabases including PubMed, Central and Embase were searched for the related clinical trials, and the references were retrieved manually; these included references were assessed qualitatively by the QUADAS-2 tool; finally the enrolled researches were qualitatively analyzed.
RESULTSA total of 15 studies consisting of 293 VTE patients met the inclusion criteria. The overall quality and the accuracy of TEG or ROTEM in predicting VTE varied a lot. Two thirds of the studies displayed that the changes of TEG parameters or ROTEM were related to the occurrence of VTE.
CONCLUSIONThe present studies showed that the TEG or ROTEM for predicting the VTE display higher difference in accuracy, therefore, the combination of TEG or ROTEM with other laboratory tests may improve the accuracy of VTE diagnosis.