Research advances in aspirin resistance.
- Author:
Xiao-Yan SI
1
;
Yong-Qiang ZHAO
Author Information
1. Department of Hematology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
- Publication Type:Journal Article
- MeSH:
Aspirin;
therapeutic use;
Drug Resistance;
Humans;
Thromboxane A2;
blood
- From:
Acta Academiae Medicinae Sinicae
2009;31(5):644-650
- CountryChina
- Language:Chinese
-
Abstract:
Aspirin is an important antithrombotic agent. However, its clinical benefit is impaired by aspirin resistance. The term of "aspirin resistance" usually refers to laboratory resistance. It can be identified by measuring thromboxane A2 or thromboxane-dependent platelet function. Clinical trials have shown that laboratory aspirin resistance is correlated with vascular events.