Relationship between children' s obstructive sleep apnea hypopnea syndrome and nasal diseases
10.3760/cma.j.issn.1673-0860.2013.06.015
- VernacularTitle:儿童阻塞性睡眠呼吸暂停低通气综合征与鼻部疾病关系的初步研究
- Author:
Ling SHEN
1
;
Yang-Yang XU
;
Zong-Tong LIN
;
Zhong-Jie YANG
Author Information
1. 350005,福建省福州儿童医院(福建医科大学教学医院)耳鼻咽喉科
- Keywords:
Sleep apnea,obstructive;
Child;
Nose diseases;
Respiratory tract infections
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2013;48(6):507-510
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between children obstructive sleep apnea hypopnea syndrome (OSAHS) and nasal diseases.Methods Three hundred and thirty-eight cases of pediatric OSAHS confirmed by polysomnography (PSG) had been enrolled as the treatment group,and divided into mild subgroup,moderate subgroup and severe subgroup according to the obstructive apnea index (OAI) and apnea hypoventilation index (AHI).The other two hundred and seven pediatric vocal cord nodule cases without OSAHS had been randomly selected as the control group.The retrospective analysis of upper respiratory tract infection frequency per year,expression levels of total IgE (tIgE) and allergenspecific IgE (slgE),results of electronic nasopharyngoscope test and nasal sinus CT scans had been performed in all the pediatric cases.The data were analyzed by SPSS 17.0.Results The upper respiratory tract infection frequency per year,ratio of cases with positive results of tlgE,ratio of cases with nasosinusitis,ratio of cases with narrow nasal cavity in the cxperiment group were respectively 8.7 ± 5.7,60.9％,79.9％ and 50.0％,while those in the control group were respectively 4.4 ± 2.6,32.8％,12.1％ and 6.3％,with significant difference between groups (t =7.578,x2 value was 41.943,237.704,110.322,all P ＜ 0.01).The multiple regression analysis indicated that,nasosinusitis and narrow nasal cavity were the two major risk factors of pediatric OSAHS (OR1 =16.008,OR2 =4.671,all P ＜ 0.01),with combined effects(OR =113.430,P ＜ 0.01).The rank test analysis in term of risk factors of severity of OSAHS had indicated that,prevalence of nasosinusitis and narrow nasal cavity were increased as risingseverity of OSAHS (x12 =21.571,x22 =17.304,all P ＜0.01).Conclusions Infection and allergy are risk factors of pediatric OSAHS.Nasosinusitis and narrow nasal cavity are two major risk factors of pediatric OSAHS,which have positive relationship with the severity of OSAHS.
