Effects of Mitogen-activated Protein Kinase Signal Pathway on Heat Shock Protein 27 Expression in Human Lens Epithelial Cells Exposed to Sodium Salicylate in vitro
10.1007/s11596-009-0323-x
- Author:
WANG ZHI
1
;
GAO RUIYING
;
HUANG YUKAN
;
TIAN BO
;
ZHOU YANLI
Author Information
1. Deppartment of Ophthalmology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
- Keywords:
sodium salicylate;
human lens epithelial cells;
mitogen-activated protein kinase;
heat shock protein
- From:
Journal of Huazhong University of Science and Technology (Medical Sciences)
2009;29(3):377-382
- CountryChina
- Language:Chinese
-
Abstract:
d that sodium salicylate can induce the expression of HSP27 in HLECs-B3. The effects are mediated, at least in part, through the activation of P38MAPK and ERK1/2 signaling pathway.