Increased Expression and Activity of MMP-9 in C-reactive Protein- induced Human THP-1 Mononuclear Cells Is Related to Activation of Nuclear Factor Kappa-B

Author: SHENG FUQIANG ^{1
,

2} ; CHENG LONGXIAN ; ZENG QIUTANG ; GAO WEN
Author Information

1. Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
2. Department of Cardiology, Affiliated Taihe Hospital, Yunyang Medical College, Shiyan 442000, China
Keywords: C-reactive protein; human THP-1 mononuclear cell; matrix metalloproteinase-9; nuclear factor kappa-B
From: Journal of Huazhong University of Science and Technology (Medical Sciences) 2009;29(4):399-403
CountryChina
Language:Chinese
Abstract: n of NF-κ3. Down-regulation of the expression and activity of MMP-9 may be a new treatment alternative for plaque stabilization by inhibiting the NF-κB activation.