Isolation and structure identification of lignans from pine needles of pinus massoniana Lamb.
- Author:
Wei-sheng FENG
1
;
Xiao-ke ZHENG
;
Yan-zhi WANG
;
Yue-feng BI
Author Information
- Publication Type:Journal Article
- MeSH: Furans; chemistry; isolation & purification; Lignans; chemistry; isolation & purification; Molecular Structure; Pinus; chemistry; Plant Leaves; chemistry; Plants, Medicinal; chemistry
- From: Acta Pharmaceutica Sinica 2003;38(12):927-930
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo study the chemical constituents from the water-extracts of pine needles of Pinus massoniana Lamb.
METHODSChromatographic techniques were used to separate and purify compounds. Their physico-chemical properties and spectral data (UV, IR, MS, 1H-1H, 13C-1H NMR, DEPT, HMBC etc.) were used to elucidate the structures.
RESULTSThree lignans were isolated from the n-BuOH fraction of water-extracts. Their structures were identified as (7S,8R)-3',4,9'-tridihydroxy-4-methoxy- 9-O-shikimoyl-7,8-dihydrobenzofuran-1'-propylneolignan (massonianoid A, I), (7S,8R)-4,9-dihydroxy-3,3'-dimethoxy-7,8- dihydrobenzofuran-1'-propylneolignan (II) and 4,4',8-trihydroxy-4,4'-dimethoxy-9-lignanolide (III).
CONCLUSIONCompound I is a new compound. While II and III were isolated from this plant for the first time.
