Pathogenesis of Parkinson's disease: oxidative stress, environmental impact factors and inflammatory processes.
- Author:
Hong YUAN
1
;
Jing-Chen ZHENG
;
Ping LIU
;
Shao-Feng ZHANG
;
Jian-Yang XU
;
Li-Min BAI
Author Information
1. Department of Integrated Traditional Chinese and Western Medicine, the General Hospital of Chinese People's Armed Police Forces, Beijing 100039, China. hongyuan6@yahoo.com
- Publication Type:Journal Article
- MeSH:
Animals;
Environmental Pollutants;
adverse effects;
Humans;
Inflammation;
immunology;
Oxidative Stress;
immunology;
Parkinson Disease;
immunology;
physiopathology
- From:
Neuroscience Bulletin
2007;23(2):125-130
- CountryChina
- Language:English
-
Abstract:
Current hypothesis of neuronal degeneration in Parkinson's disease (PD) have been proposed, including formation of free radicals and oxidative stress, mitochondrial dysfunction, excitotoxicity, trophic factor deficiency, inflammatory processes, genetic factors, environmental impact factors, toxic action of nitric oxide, apoptosis, and so on. This review mainly discussed oxidative stress, environmental impact factors, and inflammatory processes in PD.
