Clinical features of ischemic stroke in patients with nasopharyngeal carcinoma
10.3760/cma.j.issn.1673-0860.2015.05.014
- VernacularTitle:鼻咽癌合并脑梗死十例临床分析
- Author:
Yayuan LIU
1
;
Zhijian LIANG
;
Chao QIN
;
Daobin CHENG
;
Jianxiong WU
;
Lixia YU
Author Information
1. 广西医科大学第一附属医院神经内科
- Keywords:
Carcinoma,squamous cell;
Nasopharyngeal neoplasms;
Brain infarction;
clinical features;
Pathogenesis
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2015;50(5):411-414
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical features of ischemic stroke in patients with nasopharyngeal carcinoma.Methods The clinical data of the nasopharyngeal carcinoma patients with ischemic stroke treated at the First Affiliated Hospital of Guangxi Medical University between January 2006 and December 2013 were collected.Results Among 3 822 patients with nasopharyngeal carcinoma l0 patients suffered from acute ischemic stroke.The 10 patients were males and their age ranged from 39 to 70 years old,with an average age of 51 years.All of the patients were found with squamous cell carcinoma,with metastasis in 7 of them.Among the 10 patients,only 3 patients had with traditional risk factors for ischemic stroke,but no traditional risk factor was found in other 7 patients;2 patients showed single lesion in brain and 8 patients with two or more lesions due to the blockage of multiple cerebral arteries;7 patients showed an elevated plasma D-dimer level.Conclusion It is suggested that the acute ischemic stroke occurring in the patients with nasopharyngeal carcinoma commonly lacks traditional risk factors,with elevated plasma D-dimer levels and multiple lesions due to involvement of several cerebral arteries.