Changes in blood oxygen metabolism indices and their clinical significance in children with septic shock.
- Author:
Ling-Yang XU
1
;
Ding XU
Author Information
1. Department of Pediatrics, Second Hospital of Lanzhou University, Lanzhou 730000, China. 604763995@qq.com.
- Publication Type:Journal Article
- MeSH:
Carbon Dioxide;
blood;
Humans;
Lactic Acid;
metabolism;
Metabolic Clearance Rate;
Oxygen;
blood;
Shock, Septic;
metabolism
- From:
Chinese Journal of Contemporary Pediatrics
2017;19(10):1124-1128
- CountryChina
- Language:Chinese
-
Abstract:
The key to the treatment of septic shock is to provide adequate oxygen supply and improve tissue perfusion. Lactate and central venous oxygen saturation (ScvO) are commonly used as the indices of oxygen metabolism, but tissue hypoxia may still exist even when lactate and ScvOare within the normal range. Arteriovenous difference in carbon dioxide partial pressure (COgap) can accurately reflect oxygen delivery when ScvOis in the normal range. This article reviews the advantages and shortages of lactate, lactate clearance rate, ScvO, and COgap in evaluating tissue hypoxia, in order to provide a reference for treatment and severity evaluation of septic shock.
