Research advances in the mechanism of congenital heart disease induced by pregestational diabetes mellitus.
- Author:
Jie WANG
1
;
Feng WANG
;
Yong-Hao GUI
Author Information
1. Department of Cardiovascular Medicine, Children's Hospital of Fudan University, Shanghai 200023, China. yhgui@shmu.edu.cn.
- Publication Type:Journal Article
- MeSH:
Animals;
Apoptosis;
Cell Movement;
Female;
Heart Defects, Congenital;
etiology;
Humans;
Neural Crest;
physiology;
Pregnancy;
Pregnancy in Diabetics;
Reactive Oxygen Species;
metabolism
- From:
Chinese Journal of Contemporary Pediatrics
2017;19(12):1297-1300
- CountryChina
- Language:Chinese
-
Abstract:
Congenital heart disease (CHD) is the most common birth defect at present and has a complex etiology which involves the combined effect of genetic and environmental factors. Pregestational diabetes mellitus is significantly associated with the development of CHD, but the detailed mechanism remains unknown. This article reviews the research advances in the molecular mechanism of CHD caused by pregestational diabetes mellitus.
