Application of real world study in neonatal medicine.
- Author:
Yuan SHI
1
;
Yan-Ru CHEN
;
Long CHEN
Author Information
1. Department of Neonatology, Children's Hospital of Chongqing Medical University, Chongqing 400014, China. petshi530@vip.163.com.
- Publication Type:Journal Article
- MeSH:
Humans;
Infant, Newborn;
Neonatology;
Noninvasive Ventilation;
Practice Guidelines as Topic;
Pragmatic Clinical Trials as Topic;
Randomized Controlled Trials as Topic;
methods
- From:
Chinese Journal of Contemporary Pediatrics
2018;20(3):169-173
- CountryChina
- Language:Chinese
-
Abstract:
Real world study (RWS) has attracted more and more attention of neonatologists since it involves less clinical intervention and is closer to actual clinical conditions. Generally speaking, RWS means to select treatment measures based on the internal efficacy and safety verified by randomized controlled trials (RCTs), more representative samples, and patients' actual conditions and their guardians' will and conduct follow-up evaluation of short- and long-term outcomes, in order to further evaluate the external efficacy and safety of interventional measures. Most guidelines for clinical practice are based on RCTs and lack the support of real world data. Strengthening of neonatal RWS helps to make these guidelines more practical and thus promotes the development of neonatal medicine.
