Clinical Benefit of Cryoderm in Full Thickness Burns.
- Author:
Young Min KIM
1
;
Hyeong Tae YANG
;
Hae Jun LIM
;
Dohern KIM
;
Jun HUR
;
Jong Hyun KIM
;
Yong Suk CHO
;
Wook CHUN
Author Information
1. Department of Burn Surgery, Hangang Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea. chun0414@hallym.or.kr
- Publication Type:Original Article
- Keywords:
CryoDerm;
CGbio;
Artificial dermis;
Full thickness burns
- MeSH:
Animals;
Ankle;
Body Surface Area;
Burns;
Cadaver;
Contracture;
Elbow;
Epidermis;
Fibroblasts;
Follow-Up Studies;
Foot;
Hand;
Hip Joint;
Humans;
Joints;
Knee Joint;
Neck;
Shoulder;
Skin;
Transplantation, Homologous;
Transplants;
Wrist
- From:Journal of Korean Burn Society
2012;15(2):121-126
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: CryoDerm (CGbio) is derived donated human skin. After removing epidermis and fibroblast of dermal layer, it preserved with cryo-preservation technique using control rate freezer system. To prevent post burn joint contracture in massive burns, we have used CryoDerm in acute stage. METHODS: From January of 2010 to July of 2012, 50 patients who undergone CryoDerm graft with split thickness skin graft were reviewed. The operative method was as follows: 1) Early wound excision and or cadaveric allograft skin coverage was performed within 5 days after burn injury 2) 2~3 weeks after wound excision, split thickness skin graft was performed with CryoDerm graft. Then graft take rate was investigated by inspection. Follow up duration was 3~32 months. RESULTS: Mean age of patients was 42.2 (2~70) years. Mean percentage of total body surface area burned was 27.22% (1~61%). Among 50 patients, 98 joints was operated including 14 hands, 4 wrists, 10 shoulders, 23 elbows, 4 necks, 3 hip joints, 31 knee joints and 9 ankles and feet. Total used graft size of Cryoderm was 10,945 cm2. Average take rate was near 100%. CONCLUSION: Cryoderm graft with split thickness skin graft can be used as a safe and effective operative method for one stage operation in acutely burned patients.
