Detection and measurement of interleukin-8 in peri-implant crevicular fluid.
- Author:
De-rong ZOU
1
;
Hong ZHU
;
Xiao-hui QU
Author Information
- Publication Type:Journal Article
- MeSH: Dental Implants; Gingival Crevicular Fluid; Humans; Interleukin-8; Prostheses and Implants
- From: West China Journal of Stomatology 2005;23(4):292-294
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEGingival crevicular fluid (GCF) analysis of various inflammatory mediators has been investigated as a means of providing objective criteria of peri-implant tissue health. In this report, the crevicular fluid levels of interleukin-8 (IL-8), GCF volume and clinical parameters were studied.
METHODSGCF was sampled from 35 healthy and 35 inflamed sites of implantation patients. IL-8 levels were analysed using ABC-ELISA. Clinical parameters were measured, and data analysis was performed using the software package SPSS10.0.
RESULTSSignificant difference was observed between healthy implant sites and peri-implantitis sites. GCF volume was positively correlated with PD, PI, GI and MOB. The total amount of IL-8 was positively correlated with PD and GI.
CONCLUSIONThis investigation suggested that GCF volume and IL-8 cytokine may be of value as a diagnostic and prognostic marker for peri-implantitis.