Evaluation on cytotoxicity of a new nano-hydroxyapatite as root canal filling sealer.
- Author:
Ping LI
1
;
Li-ying XIAO
;
Wei LI
;
Hong TAN
;
Yun-mao LIAO
;
Ming-long YUAN
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Cell Survival; Dental Pulp Cavity; Durapatite; Mice; Root Canal Filling Materials; Zinc Oxide-Eugenol Cement
- From: West China Journal of Stomatology 2005;23(5):427-430
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluated the cytotoxicity of a new nano-hydroxyapatite (n-HA) root canal sealer.
METHODSIn this study, the cytotoxicity was evaluated by the method of MTT assay in vitro, and culture medium F12 as control, three concentrations of the soaking material cultured with mouse osteoblast separately, to test the cell relative growth rate (RGR) of every group.
RESULTSThe toxicity graduation of the n-HA root canal sealer tends to 0 with the culture time increasing. The cell survival rate of n-HA root canal sealer showed high relatively. The OD value of cell was similar for the negative control and the extracts (P > 0.05).
CONCLUSIONThe result indicated that n-HA root canal sealer was compatible with the testcells.
