310 cases of thymectomy for myasthenia gravis.
- Author:
Yong-zhong WANG
1
;
Wen-jun ZHEN
;
Wei-zhong YAN
;
Hong-feng TONG
;
Yao-guang SUN
;
Hong GUO
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myasthenia Gravis; surgery; Perioperative Care; Prognosis; Retrospective Studies; Thymectomy; methods; Treatment Outcome; Young Adult
- From: Chinese Journal of Surgery 2003;41(8):607-609
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the clinical characteristics and long-term outcome of 310 cases of thymectomy for myasthenia Gravis.
METHODSThe data of 310 patients with thymectomy were analyzed retrospectively to study the patient selection, operative techniques, perioperative management and results for myasthenia Gravis. Absolute and relative scores for clinical evaluation were used as the criteria to determine the therapeutic effects of thymectomy.
RESULTSThere were no operative death and postoperative complication rates were 8.7% (27/310). The extra anatomic thymic tissue was found in up to 38.7% (120/310) patients and thymus hyperplasia occurred in 92.9% (288/310) cases. 92.6% (287/310) postoperative patients were followed up for 3 or more months; the percentage of patients being remitted, essentially remitted, significantly effective, effective and non-effective were 7.1% (22/310), 11.3% (35/310) 40.0% (124/310), 27.1% (84/310), 7.1% (22/310) respectively. The total long-term effective rate was 85.5% (265/310). The effective rate for type I, IIa, IIb, III, IV was 90.9% (20/22), 97.6% (40/41), 95.3% (162/170), 80.6% (29/36), 77.8% (14/18) respectively.
CONCLUSIONSGeneralized typed and properly selected recurrent ocular-typed patients with Myasthenia Gravis undergoing extensive thymectomy would have good long-term outcomes.
