The clinical evaluation of patients with pituitary adenomas undergone transsphenoidal microsurgery.
- Author:
Yao ZHAO
1
;
Shi-qi LI
;
Liang-fu ZHOU
;
Yong-fei WANG
;
Xue-fei SHOU
;
Pi-feng JIA
Author Information
- Publication Type:Journal Article
- MeSH: Adenoma; surgery; Adolescent; Adult; Aged; Aged, 80 and over; Child; Female; Follow-Up Studies; Humans; Male; Microsurgery; methods; Middle Aged; Neurosurgical Procedures; methods; Pituitary Neoplasms; surgery; Retrospective Studies; Sphenoid Sinus; surgery; Treatment Outcome; Young Adult
- From: Chinese Journal of Surgery 2003;41(8):610-613
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the overall effect of transsphenoidal microsurgery for pituitary adenomas in recent 5 years and to discuss the surgical technique, application of new technology and postoperative follow-up results.
METHODSThe clinical presentation, image characteristics, endocrinal findings, pathological types, tumor removal percentage, postoperative complication and follow-up of 1 462 patients with pituitary adenomas who underwent the transsphenoidal microsurgery from 1997 to 2002 were analysed retrospectively.
RESULTSTotal rate of tumor removal for the patients achieved 97.0% in the patients with Hardy I adenomas, 95.2% with Hardy II, 90.5% with Hardy III, and 47.4% with Hardy IV respectively. A significant postoperative improvement both in clinical symptoms and endocrinal parameters was achieved. The tumor recurrence rate was 0.3%.
CONCLUSIONSWith the improvement of microsurgical technique and application of novel technology, the indication of transsphenoidal microsurgery for pituitary adenomas was increasingly extended. Endoscope and(/or) neuronavigation-assisted microsurgery via transsphenoidal approach should be of the first choice for the treatment of pituitary adenomas. The routine postoperative radiotherapy is not required for patients with total tumor removal.
