Experience on transplantation of auto-pulmonary graft treating with congenital aortic disease.
- Author:
Wen-bin LI
1
;
Jian-qun ZHANG
;
Hai-bo ZHOU
;
Sheng-xun WANG
;
Wei LIU
;
Ping BO
;
Hui-li GAN
;
Bin MAO
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aortic Valve Insufficiency; surgery; Aortic Valve Prolapse; surgery; Aortic Valve Stenosis; surgery; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Male; Pulmonary Valve; transplantation; Transplantation, Autologous
- From: Chinese Journal of Surgery 2004;42(8):455-457
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo summarize the experience on auto-pulmonary transplantation (Ross procedure) treating with congenital aortic disease.
METHODSFrom October 1994 to November 2003, 20 cases of Ross procedure were performed to treat with congenital aortic disease, Male: 15 cases; Female: 5 cases; age: 25 years;
DIAGNOSIScongenital heart disease (CHD), aortic abnormalities: 12 cases; aortic valve prolapse: 5 cases; aortic valve hypogenesis: 3 cases; combined with subacute bacterial endocarditis (SBE): 4 cases, and ventricle septal defect (VSD): 2 cases; UCG showed aortic stenosis(AS) and/or aortic insufficience (AI) (moderate to severe), Left ventricle diastole diameter (LVDD): (60.51 +/- 11.87) mm, the grade pressure across aortic valve: (27.04 +/- 6.80) mmHg, heart function (NYHA): Class II: 13 cases; Class III: 3 cases; all cases were performed under CPB and moderate hypothermia, the operation procedure was following: (1) taking off auto-pulmonary artery valve; (2) removing dysfunctional aortic valve and auto-transplantation of pulmonary valve on aortic root; (3) putting a pulmonary homograft to rebuild right ventricular outflow tract.
RESULTSThe mortality was 0 during stay at hospital, aortic valve function were all normal, LVDD decreased significantly (t = 3.4007, P = 0.0008), the grade pressure across aortic valve was in normal limitation, (6.8 +/- 0.19) mmHg. Follow-up showed heart function was in Class I (NYHA), aortic and pulmonary valve function was very well.
CONCLUSIONRoss procedure is a kind of effective alterative operation for treating with congenital aortic valve disease, with good short and middle term results.
