Research progress of chemical composition of taxane in Taxus canadensis and medicine source crisis solution.
- Author:
Chun YANG
;
Ling-Yi KONG
;
Jun-Song WANG
- Publication Type:Journal Article
- MeSH:
Animals;
Bridged-Ring Compounds;
chemical synthesis;
chemistry;
pharmacology;
Humans;
Molecular Structure;
Plant Extracts;
chemical synthesis;
chemistry;
pharmacology;
Plants, Medicinal;
chemistry;
Taxoids;
chemical synthesis;
chemistry;
pharmacology;
Taxus;
chemistry
- From:
China Journal of Chinese Materia Medica
2014;39(11):1961-1971
- CountryChina
- Language:Chinese
-
Abstract:
Taxus canadensis distributed mainly in North America, such as northern Minnesota, Newfoundland, south to Wisconsin and Pennsylvania. Its composition has been shown to be very different from other species, and in recent years, some new skeletons also have been found in Canada yew. Through analysis of the taxanes content on various Taxus plants containing taxanes, the results showed a higher content of taxol in T. canadensis. Based on the current research on T. canadensis (from the research results of the author in recent years, as well as from studies of scholars in the field), the paper outlined the research progress in recent years on the chemical constituents of taxane of T. canadensis and the spectral characteristics of various types of compounds. Besides, this paper analyzed the present research about solutions for the taxol drug source crisis.
