Sulfation of naringenin by Mucor sp.
- Author:
Fei-Ying RUAN
;
Ri-Dao CHEN
;
Jian-Hua LI
;
Min ZHANG
;
Ke-Bo XIE
;
Yan WANG
;
Ru FENG
;
Jun-Gui DAI
- Publication Type:Journal Article
- MeSH:
Biotransformation;
Drugs, Chinese Herbal;
chemistry;
metabolism;
Flavanones;
chemistry;
metabolism;
Magnetic Resonance Spectroscopy;
Molecular Structure;
Mucor;
metabolism;
Sulfates;
metabolism
- From:
China Journal of Chinese Materia Medica
2014;39(11):2039-2042
- CountryChina
- Language:Chinese
-
Abstract:
Naringenin (1) was transformed to three metabolites (2-4) by Mucor sp. Based on LCMS(n)-IT-TOF and NMR spectroscopic data, 2-4 were identified as naringenin-7-O-sulphate, naringenin-4'-O-sulphate, and naringenin-5-O-sulphate, respectively. These results might provide hints to the mammalian/human metabolism of naringenin.
