Simultaneous liver-kidney transplantation in polycystic kidney and hepatic disease with kidney and liver failure.
- Author:
Li-xin YU
1
;
Yan-bin WANG
;
Jian XU
;
Wen-feng DENG
;
Shao-jie FU
;
Chuan-fu DU
;
Yi-bin WANG
;
Yun MIAO
;
Gui-rong YE
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Female; Follow-Up Studies; Humans; Kidney Transplantation; Liver Diseases; complications; surgery; Liver Failure; etiology; surgery; Liver Transplantation; Male; Middle Aged; Polycystic Kidney Diseases; complications; surgery; Renal Insufficiency; etiology; surgery; Retrospective Studies; Treatment Outcome
- From: Chinese Journal of Surgery 2009;47(20):1557-1559
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo review the clinical experiences concerning simultaneous liver-kidney transplantation in polycystic kidney and hepatic disease with kidney and liver failure.
METHODSThis study involved 8 cases of simultaneous liver-kidney transplantation in polycystic kidney and hepatic disease with kidney and liver failure. There were 5 male and 3 female patients, aged from 41 to 67 years old with a mean of 52.8 years old. Six cases transplanted kidney after liver with orthotopic liver transplantation, and 2 cases transplanted liver after kidney with piggy-back liver transplantation. The acute rejections, complications, liver function, kidney functions, and survival rates of patient/liver/kidney were recorded.
RESULTSWithin the follow-up of 28 to 65 months, all 8 patients are still alive with normal liver and kidney functions: 2 living more than 5 years, 2 living more than 4 years and 4 living more than 2 years. 2 cases of pleural effusion and 1 case of pneumonia were complications after operation, which had been cured successfully. No acute rejection of allograft was observed.
CONCLUSIONSSimultaneous liver-kidney transplantation is a safe and effective treatment for polycystic kidney and hepatic disease with kidney and liver failure.