Study on the Platelet Survival Time in the Patients with Coronary Artery Disease.
10.4070/kcj.1985.15.4.625
- Author:
Hie Chull SON
;
Yeong Chun LEE
;
Yeong Sook RHA
;
Ja Cheon KIM
;
In Soon KWON
;
Yung LEE
;
Jeong Hyoun PARK
;
Hyoun Chan CHO
- Publication Type:Original Article
- MeSH:
Angina Pectoris;
Blood Platelets*;
Coronary Artery Disease*;
Coronary Vessels*;
Hematology;
Humans;
Infarction;
Myocardial Infarction;
Platelet Activation;
Radioisotopes
- From:Korean Circulation Journal
1985;15(4):625-632
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
To evaluate the platelet activation in vivo in the patients with coronary artery disease Indium-111 labeled autologus platelet survival time was measured. Platelet survival determinations were made according to a modified method for radioisotope platelet survival studies recommended by the Panel on Diagnostic Application of Radioisotopes in Hematology of the International Committee for Standardization in Hematology. Autologous platelets were labeled with 111 In-oxine utilizing a similar method used at the Mallinckrodt Institute of Radiology. The results are summarized as follows : 1) In the patients with coronary artery disease, especially acutemyocardial infarction, the mean platelet survival time was significantly shorter than that of the normal controls(P<0.05). 2) The mean platelet survival time did not differ significantly between patients with acute myocardial infarction and angina pectoris. 3) The mean platelet survival time did not differ significantly between nonsmoker and smoker in the patients with coronary artery disease.
