Posttransplant Lymphoproliferative Disorder without Epstein-Barr Virus Presented as Small Bowel Perforation in Renal Transplant Recipient: A Case Report.
10.4285/jkstn.2013.27.3.138
- Author:
Min Jhi KIM
1
;
Hongjin SHIM
;
Ji Young JANG
;
Su Hyung LEE
;
Kyu Ha HUH
;
Yu Seun KIM
;
Jae Gil LEE
Author Information
1. Department of Surgery, Yonsei University College of Medicine, Seoul, Korea. jakii@yuhs.ac
- Publication Type:Case Report
- Keywords:
Posttransplant lymphoproliferative disease;
Small bowel perforation;
Kidney transplantation
- MeSH:
Epstein-Barr Virus Infections;
Gastrointestinal Tract;
Herpesvirus 4, Human;
Kidney Transplantation;
Lymph Nodes;
Lymphoproliferative Disorders;
Risk Factors;
Transplants
- From:The Journal of the Korean Society for Transplantation
2013;27(3):138-142
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Posttransplant lymphoproliferative disorder (PTLD) is documented as one of the serious complications leading to mortality particularly in organ transplant recipients receiving immunosuppressive therapy. Extant literature confirms beyond doubt that the most common site of involvement of PTLD is lymph nodes, and rarely involved is the gastrointestinal tract. It is a well-known fact that Epstein-Barr virus (EBV) is a risk factor for PTLD development. In this study, we report a case of PTLD presented as small bowel perforation without EBV infection after long-term immunosuppressive therapy in a renal transplant recipient.