Therapy and Prophylaxis for superficial Bladder Tumors: Doxorubicin and Thio-tepa.
- Author:
Woo Soon PARK
1
;
Sung Choon LEE
Author Information
1. Department of Urology, Keimyung University, School of Medicine, Taegu, Korea.
- Publication Type:Original Article
- Keywords:
superficial bladder tumor;
doxorubicin;
thiotepa
- MeSH:
Doxorubicin*;
Dysuria;
Follow-Up Studies;
Hematuria;
Recurrence;
Thiotepa*;
Urethral Stricture;
Urinary Bladder Neoplasms*;
Urinary Bladder*;
Urination
- From:Korean Journal of Urology
1984;25(2):149-153
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
20 cases of study group whose follow-up period is over 6 months among 22 cases of bladder tumors treated with doxorubicin instillation following TUR during the period from December, 1981 through December, 1983 were compared with 30 cases of controlled group whose follow-up period is over 6 months among 32 cases of bladder tumors treated with thio-tepa instillation following TUR during the period from January, 1978 through June, 1981. Following result were obtained. 1. Recurrence rate In TUR + doxorubicin, 25%, In TUR+thio-tepa,30% 2. Interval between TUR & the first recurrence: In TUR + doxorubicin, average 9 months, In TUR + thio-tepa, average 8.1 months 3. Complication: In TUR + doxorubicin, painful urination in 2 cases(10%), In TUR + thio-tepa, hematuria, dysuria, painful urination, and urethral stricture in 8 cases(26.7%).