A Clinical Study of Oral Fosfomycin(Fosmycin) in the Treatment of Lower Urinary Tract Infection.
- Author:
Sang Eun LEE
1
;
Hwang CHOI
;
Young Kyoon KIM
Author Information
1. Department of Urology, College of Medicine, Seoul National University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
fosfomycin;
UTI
- MeSH:
Bacteriuria;
Dizziness;
Epididymitis;
Fosfomycin;
Headache;
Humans;
Male;
Urinary Tract Infections*;
Urinary Tract*
- From:Korean Journal of Urology
1984;25(2):167-172
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Twenty-four patients with lower urinary tract infection have been treated with 7-day course of oral fosfomycin and following results were obtained. 1. Clinical result of 11 cases of acute uncomplicated infection was excellent in 10 and good in 1, efficacy rate being 100%. 2. Clinical result of 7 cases of complicated infection was excellent in 4, good in 1 and poor in 2, efficacy rate being 71%. 3. Clinical result of 4 cases of asymptomatic bacteriuria was excellent in 1 and poor in 3, efficacy rate being 25%. 4. Both 1 case of NGU and 1 case of acute epididymitis probably caused by Chlamydial or Mycoplasmal infection were not improved. 5. No significant side effect except mild headache and dizziness was observed. In conclusion, oral fosfomycin is a safe and very useful drug especially in the treatment of acute uncomplicated lower urinary tract infection.