Progress in the personalized medicine using pharmacometabonomics.
- Author:
Qing HUANG
;
Ji-ye A
;
Guo-Hua ZHOU
- Publication Type:Journal Article
- MeSH:
Humans;
Metabolome;
Metabolomics;
Pharmacogenetics;
Precision Medicine;
methods
- From:
Acta Pharmaceutica Sinica
2014;49(11):1491-1497
- CountryChina
- Language:Chinese
-
Abstract:
Pharmacometabonomics, as an emerging branch of system biology, has been increasingly used in personalized medicine and showed broad prospects. By means of metabonomics, the complicated and detailed metabolic profile of the patient is described, thus providing more detailed description of the disease phenotype. With this understanding, response of different individuals to the drugs are predicted or evaluated through inherent genetic information of the individual combined with the environmental factors. As a result, appropriate drugs and dosage are chosen, which greatly promotes the realization of the individualized therapy goals. This article describes the emerging field of pharmacometabonomics, and the research results of personalized medicine based on the pharmacometabonomics in recent years are reviewed in detail.
