The compounds from n-butanol fraction of Alpinia oxyphylla.
- Author:
Bin-Bin XIE
;
Lei HOU
;
Bao-Lin GUO
;
Wen-Hua HUANG
;
Jing-Guang YU
- Publication Type:Journal Article
- MeSH:
1-Butanol;
Alpinia;
chemistry;
Chromatography, High Pressure Liquid;
Fruit;
chemistry;
Phytochemicals;
chemistry;
isolation & purification;
Sesquiterpenes;
chemistry;
isolation & purification
- From:
Acta Pharmaceutica Sinica
2014;49(11):1569-1573
- CountryChina
- Language:Chinese
-
Abstract:
Nine compounds were isolated from the n-butanol fraction of 95% ethanol extract of the fruit of Alpinia oxyphylla Miq. with a combination of various chromatographic approaches, including MDS resin, silica gel, reverse phase C18 and preparative HPLC. On the basis of spectroscopic data analysis, they were elucidated as (1R, 4R, 10R)-1β, 4α-dihydroxy-11, 12, 13-trinor-5, 6-eudesmen-7-one (1), 1β, 4β-dihydroxy-11, 12, 13-trinor-8, 9-eudesmen-7-one (2), oxyphyllenone A (3), oxyphyllenone B (4), rhamnocitrin (5), staphylionoside D (6), benzyl-1-O-β-D-glucopyranoside (7), 2-O-β-D-glucopyranosyl-(1S)-phenylethylene glycol (8), and (S)-1-phenylethyl-β-D-glucopyranoside (9). Among them, compound 1 is a new sesquiterpene, named as oxyphyllenone C; compounds 8 and 9 are new natural products; compounds 2 and 6 were isolated from the genus Alpinia for the first time, and compound 7 was isolated from A. oxyphylla for the first time.
