Surgical site infection in pancreas surgery and the use of perioperative antibiotics.
- Author:
Ai WANG
1
;
Jiong ZHOU
;
Xiao-Jun MA
;
Li-li DONG
;
Gui-ping LI
Author Information
- Publication Type:Journal Article
- MeSH: Anti-Bacterial Agents; therapeutic use; Antibiotic Prophylaxis; Drug Resistance, Microbial; Humans; Perioperative Care; Surgical Wound Infection; microbiology; prevention & control; Time Factors
- From: Acta Academiae Medicinae Sinicae 2007;29(4):566-570
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo analyze the pathogen profiles and the use of perioperative antibiotics after surgical site infection (SSI) in pancreas operation.
METHODWe retrospectively analyzed the pathogen profiles and the use of perioperative antibiotics in 48 SSI patients who received pancreas operations from Jan 2001 to Dec 2005.
RESULTSTotally 79 strains of pathogens (74 strains of bacteria) were isolated, including 17 strains of methicillin-resistant Staphylococcus aureus (MRSA), 17 strains of enterococcus species, 12 strains of Escherichia species, and 5 strains of enterobacteriaceae. Combination of the third generation of cephalosporins and antianaerobic agents were the main prophylactic therapies, with an average duration of (4.7 +/- 1.2) days. Most SSI episodes happened 6-14 days postoperatively (median 9 days). Celiac infections were most common (n=39). Therapeutic antibiotics gave priority to combined-antibiotics of the third cephalosporins and antianaerobic antibiotics, glycopeptides and carbapenems.
CONCLUSIONSSSI commonly occurs on the 6-14 postoperative day, with MRSA and enterococci as the common pathogens of SSI after pancreas surgery. Antibiotic resistance should be considered when applying prophylactic therapies.
