Role of contrast-enhanced ultrasound in the differentiation of solid focal lesions of pancreas.
- Author:
Xiao-Yan XIE
1
;
Er-Jiao XU
;
Hui-Xiong XU
;
Zuo-Feng XU
;
Guang-Jian LIU
;
Yan-Ling ZHENG
;
Jin-Yu LIANG
;
Bei HUANG
;
Ming-De LÜ
Author Information
- Publication Type:Journal Article
- MeSH: Diagnosis, Differential; Humans; Pancreas; diagnostic imaging; Pancreatic Neoplasms; diagnostic imaging; Pancreatitis; diagnostic imaging; Retrospective Studies; Ultrasonography
- From: Acta Academiae Medicinae Sinicae 2008;30(1):35-39
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the value of contrast-enhanced ultrasound in the differential diagnosis of solid focal lesions of pancreas (s-FLPs).
METHODSWe retrospectively analyzed the clinical data of 56 s-FLPs examined with contrast agent combined with low mechanical indicators contrast-enhanced ultrasound.
RESULTSThe surrounding pancreas parenchyma enhancement time, lesion enhancement time, and peak enhancement time between different groups of s-FLPs had no significant differences (P > 0.05), while the beginning to peak enhancement time showed significant difference (P < 0.05). When using the enhancement speed as a diagnostic indicator to differentiate pancreatic carcinoma from tumor-like pancreatitis, the sensitivity, specificity, and accuracy were 90.5%, 71.4%, and 85.7% for pancreatic carcinoma and 75.0%, 91.7%, and 89.3% for tumor-like pancreatitis. When using the enhancement pattern as a diagnosis indicator to differentiate pancreatic carcinoma from tumor-like pancreatitis, the sensitivity, specificity, and accuracy were 85.7%, 78.6%, and 83.9% for pancreatic carcinoma and 75.0%, 100%, and 94.6% for tumor-like pancreatitis. When different indicators were combined, enhancement pattern and enhancement speed showed the best diagnostic results; however, the Youden index was not improved.
CONCLUSIONSDifferent s-FLPs show different enhancement findings on contrast-enhanced ultrasound. The enhancement pattern and enhancement speed are the most useful diagnostic indicators.