Analysis of 993 cases of fetal malformations from 1999 to 2006.
- Author:
Sheng-Li LI
1
;
Xiu-Lan CHEN
;
Shu-Yuan OUYANG
;
Yuan YAO
;
Bo GONG
;
Cong-Ying CHEN
;
Xiao-Dong YANG
;
Zhi-Lian XIAO
;
Yu-Mei LIAO
Author Information
- Publication Type:Journal Article
- MeSH: Congenital Abnormalities; diagnostic imaging; False Negative Reactions; Humans; Retrospective Studies; Ultrasonography, Prenatal
- From: Acta Academiae Medicinae Sinicae 2008;30(1):69-74
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the value of prenatal ultrasound in the diagnosis of fetal malformations.
METHODSWe retrospectively analyzed the clinical data of 993 cases of neonates and induced babies with malformations who were labored in our hospital from January 1999 to October 2006.
RESULTSThe incidence rate of fetal malformation was 22.5 per thousand in our study group. The detection rate of prenatal ultrasound was 79.02% (1 062/1 344), among which the detection rate of the severe malformations (87.58%, 860/982) were significantly higher than that of the minor malformations (55.80%, 202/362) (P < 0.005). The false negative rate was high for the extremity malformations (39.46%) and facial malformations (31.91%), especially the acrosclerodermas, simple cleft palates, and ear deformities.
CONCLUSIONPrenatal ultrasound is sensitive for fetal severe malformations, while the detection rate is low for fetal minor malformations.
